Monday, February 1, 2010

?, ?- Unsaturated Lactone-Nitrone Cycloadditions: a Route to the Synthesis of (±)–Tussilagin

?, ?- Unsaturated Lactone-Nitrone Cycloadditions: a Route to the Synthesis of (±)–Tussilagin

Mohammed A. Al-Nuri

1 Chemistry Department, An-Najah N. University, Nablus, West-Bank
Received : 00-00-0000 , Accepted : 00-00-0000
Language: English
Abstract

Reaction of nitrone (V with a, f1 -unsaturated lactone C.4) resulted in the isolation of a single adduct (7). The observed high regiochemical control has encouraged further explorations of natural product synthesis. A route to the synthesis of an interesting member of Pyrrolizidine- Alkaloid family; (±) -Tussilagin 90/ has been described.

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